Animals in the fight against ALS: Animals aid research

Animals are powerful tools in the study of ALS, and in recent years, the diversity of animal models has expanded substantially. With every gene defect that is identified, it has been possible to generate animal models of ALS caused by the corresponding defect. These animal models have involved mice and rats and, more recently, fruit flies and fish. Each animal offers its own particular advantages as an experimental model.

By studying animals with ALS, scientists can learn more about the process of degeneration of motor nerves in the brain and spinal cord. New discoveries and new ALS treatments can be tested very efficiently in the ALS animal models. Funds provided by the ALS Therapy Alliance and CVS/pharmacy help scientists conduct this research.