Drug delivery to the brain: Crossing the iron curtain

A major problem in treating brain disorders is getting treatments across the blood brain barrier (BBB), an iron curtain that normally prevents proteins and toxins from entering the central nervous system. To be effective in brain diseases, drugs must go from the bloodstream to the brain and spinal cord. New investigations, funded in part by the ALS Therapy Alliance, are looking for ways to engineer molecules that will navigate through the BBB.

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